Could Botox-Like shots ease debilitating CRPS pain?
NCT ID NCT07473635
First seen Mar 20, 2026 · Last updated Jun 21, 2026 · Updated 12 times
Summary
This study is testing whether a single injection of botulinum toxin (similar to Botox) around major nerves can safely reduce pain in people with Complex Regional Pain Syndrome (CRPS), a chronic condition causing severe pain and disability. Twenty adults with CRPS in one arm or leg will receive the injection and be followed for 12 weeks. The main goal is to see if the procedure is practical and safe, not yet to prove it works.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CRPS- and Nerve Pain Clinic, Rigshospitalet Glostrup
RECRUITINGGlostrup, Region Sjælland, 2600, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Incobotulinumtoxin-A (a type of botulinum toxin, like Botox)
What this could lead to
If this approach is safe and feasible, it could lead to a larger trial testing whether botulinum toxin injections can reduce pain and flare-ups in CRPS.
What could go wrong
This is a very small, early feasibility study with only 20 people. It is not designed to prove the treatment works, and there is a risk of side effects or worsening pain from the injection itself.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.