Botox vs. patch: which stops drooling better in kids with cerebral palsy?

NCT ID NCT03616067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two treatments for drooling in children with cerebral palsy: Botox injections into the salivary glands and scopolamine skin patches. Both groups also received rehabilitation therapy. The goal was to see which treatment reduced drooling more over 15 months. The trial was terminated early after enrolling only 23 children, so the results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum toxin A (Botox) injection and scopolamine (Scopoderm) patches

What this could lead to

If it works, this could point toward a more effective, longer-lasting treatment for drooling in children with cerebral palsy, improving quality of life.

What could go wrong

The trial was terminated early with only 23 participants, so results are limited. Both treatments have side effects, and the study may not provide clear answers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CEREBRAL PALSY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HM

    Marseille, France

  • APFESEAN Nantes

    Nantes, France

  • CHU d'Angers

    Angers, France

  • CHU- Estaing

    Clermont-Ferrand, France

  • CHU-Bordeaux

    Bordeaux, France

  • CHU-Grenoble

    Grenoble, France

  • CHU-Nimes

    Nîmes, France

  • Centre Médico-Chirurgical de Réadaptation des Massues

    Lyon, 69322, France

  • Centre médico- infantile

    Romagnat, France

  • Hôpital Femme Mère Enfant - HCL

    Bron, France

  • Hôpitaux de Saint-Maurice

    Saint-Maurice, France