Botox vs. patch: which stops drooling better in kids with cerebral palsy?

NCT ID NCT03616067

Terminated Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two treatments for drooling in children with cerebral palsy: Botox injections into the salivary glands and scopolamine skin patches. Both groups also received rehabilitation therapy. The goal was to see which treatment reduced drooling more over 15 months. The trial was terminated early after enrolling only 23 children, so the results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum toxin A (Botox) injection and scopolamine (Scopoderm) patches
What this could lead to: If it works, this could point toward a more effective, longer-lasting treatment for drooling in children with cerebral palsy, improving quality of life.
What could go wrong: The trial was terminated early with only 23 participants, so results are limited. Both treatments have side effects, and the study may not provide clear answers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL PALSY

Contacts and locations

Locations

AP-HM

Marseille, France
APFESEAN Nantes

Nantes, France
CHU d'Angers

Angers, France
CHU- Estaing

Clermont-Ferrand, France
CHU-Bordeaux

Bordeaux, France
CHU-Grenoble

Grenoble, France
CHU-Nimes

Nîmes, France
Centre Médico-Chirurgical de Réadaptation des Massues

Lyon, 69322, France
Centre médico- infantile

Romagnat, France
Hôpital Femme Mère Enfant - HCL

Bron, France
Hôpitaux de Saint-Maurice

Saint-Maurice, France

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