New drug combo tested for Tough-to-Treat cancers

NCT ID NCT02211755

First seen Oct 31, 2025 · Last updated Jun 12, 2026 · Updated 35 times

Summary

This early-phase study tested a combination of two cancer drugs, bortezomib and clofarabine, in 28 adults with advanced solid tumors, lymphomas, or myelodysplastic syndromes that had stopped responding to standard treatments. The main goal was to find the safest dose and check for side effects. Participants received the drugs in 21-day cycles, with close monitoring for safety and tumor response.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.