Can freezing bone tumors stop cancer in its tracks?

NCT ID NCT06480955

Recruiting now Disease control Sponsor: Cardiovascular and Interventional Radiological Society of Europe Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 50 people with cancer that has spread to the bones (bone metastases) to see if freezing those tumors with a special probe (cryoablation) can control them. The goal is to prevent local tumor growth, ease pain, and improve quality of life. Participants have limited spread (oligometastatic disease) and are being treated with a curative intent, but the study is observational, meaning it only watches outcomes without comparing to another treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cryoablation (freezing tumor cells using a device from Boston Scientific)
What this could lead to: If successful, this could show that freezing bone metastases helps control local tumor growth and reduces pain, offering a treatment option for people with limited spread of cancer.
What could go wrong: This is an early observational study with only 50 participants, so results may not apply to everyone. Cryoablation carries risks like bleeding, infection, or nerve damage, and it may not prevent new metastases elsewhere.

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Conditions

The condition(s) this trial relates to.

metastatic carcinoma in the bone

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE METASTASES

Contacts and locations

Locations

CHRU de Strasbourg
RECRUITING

Strasbourg, 67200, France
CHUV-Lausanne University Hospital
RECRUITING

Lausanne, 1011, Switzerland
Hospital Universitario y Politécnico La Fe
RECRUITING

Valencia, 46026, Spain
Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France
Institute Bergonié
RECRUITING

Bordeaux, 33076, France

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