Could a simple pill replace the needle for kids with bone infections?

NCT ID NCT04538053

Recruiting now Disease control Sponsor: Murdoch Childrens Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving children with bone and joint infections antibiotics only by mouth works just as well as starting with IV antibiotics for a few days and then switching to pills. About 285 children aged 1 to 18 from hospitals in Australia and New Zealand will take part. The goal is to see if the simpler oral-only approach leads to full recovery after 3 months.

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Conditions

The condition(s) this trial relates to.

bacterial arthritis infective arthritis osteomyelitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE AND JOINT INFECTION BONE INFECTION OSTEOMYELITIS SEPTIC ARTHRITIS

Contacts and locations

Locations

Christchurch Hospital
RECRUITING

Christchurch, 8011, New Zealand
John Hunter Children's Hospital
RECRUITING

New Lambton Heights, New South Wales, 2305, Australia
Nepean Hospital
RECRUITING

Kingswood, New South Wales, 2747, Australia
Perth Children's Hospital
RECRUITING

Perth, Western Australia, 6009, Australia
Queensland Children's Hospital
RECRUITING

Brisbane, Queensland, 4101, Australia
Royal Darwin Hospital
RECRUITING

Darwin, Northern Territory, 0811, Australia
Sydney Children's Hospital Network
RECRUITING

Sydney, New South Wales, 2031, Australia
The Children's Hospital at Westmead
ACTIVE_NOT_RECRUITING

Sydney, New South Wales, 2145, Australia
The Royal Children's Hospital
RECRUITING

Melbourne, Victoria, 3051, Australia
Women's and Children's Hospital
RECRUITING

Adelaide, South Australia, 5006, Australia

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