New Blood-Derived graft may improve dental implant success

NCT ID NCT07584629

Completed Disease control Sponsor: Universitaire Ziekenhuizen KU Leuven Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two ways to rebuild jawbone for dental implants in 12 patients. One method used a blood-derived graft (LPRF block), the other used a mix of the patient's own bone and cow bone mineral. Over 25 months, researchers measured bone growth and implant survival. The goal was to see which approach works better for creating a strong foundation for implants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LPRF block (a blood-derived graft) and a mixture of autogenous bone with deproteinized bovine bone mineral
What this could lead to: If successful, this could point toward a better, less invasive way to rebuild jawbone for dental implants, potentially improving implant success and reducing complications.
What could go wrong: This is a very small study (12 patients) and only compares two graft types. Results may not apply to everyone, and bone grafting always carries risks like infection or graft failure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR BONE RESORPTION

Contacts and locations

Locations

UZ Leuven

Leuven, Vlaams-Brabant, 3000, Belgium

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