Could a gel replace bone grafts for tooth socket healing?

NCT ID NCT07496437

Not yet recruiting Disease control Sponsor: Medical University of Vienna Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a gel made from cross-linked hyaluronic acid (a natural substance) to standard bone grafting for preserving the jawbone after a tooth is pulled. Forty-eight adults needing a tooth extraction and later a dental implant will be randomly assigned to receive either the gel or a bone graft. The main goal is to see if the gel works as well as the bone graft at preventing bone loss over 4 months, with fewer downsides like long healing times.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cross-linked hyaluronic acid
What this could lead to: If it works, this could offer a simpler, faster-healing alternative to bone grafts for preserving jawbone after tooth extraction, potentially reducing the need for additional grafting before dental implants.
What could go wrong: This is a small, early-stage trial with only 48 participants, and it tests non-inferiority—meaning it aims to show the new method is not worse than the standard, not necessarily better. The results may not apply to all teeth or patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR BONE RESORPTION ALVEOLAR RIDGE ENLARGEMENT HYALURONIC ACID TOOTH EXTRACTION

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