Could a gel replace bone grafts for tooth socket healing?

NCT ID NCT07496437

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study compares a gel made from cross-linked hyaluronic acid (a natural substance) to standard bone grafting for preserving the jawbone after a tooth is pulled. Forty-eight adults needing a tooth extraction and later a dental implant will be randomly assigned to receive either the gel or a bone graft. The main goal is to see if the gel works as well as the bone graft at preventing bone loss over 4 months, with fewer downsides like long healing times.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cross-linked hyaluronic acid

What this could lead to

If it works, this could offer a simpler, faster-healing alternative to bone grafts for preserving jawbone after tooth extraction, potentially reducing the need for additional grafting before dental implants.

What could go wrong

This is a small, early-stage trial with only 48 participants, and it tests non-inferiority—meaning it aims to show the new method is not worse than the standard, not necessarily better. The results may not apply to all teeth or patients.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.