Blood test may spot hidden cancer after abdominal surgery

NCT ID NCT04157322

Ongoing Diagnosis Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a blood test can detect if cancer comes back after surgery for colorectal or appendix cancer that spread to the abdomen. Researchers will collect blood samples from 55 patients before and after surgery to measure DNA changes. The goal is to see if this test is better than standard tumor markers at finding recurrence within one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this blood test could help doctors find cancer recurrence earlier than current methods, potentially improving treatment timing.
What could go wrong: This is a small, early-stage study with only 55 participants. The test may not be more accurate than existing tumor markers, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

appendiceal neoplasm appendix adenocarcinoma appendix cancer colorectal adenocarcinoma colorectal cancer colorectal neoplasm goblet cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APPENDIX CANCER COLORECTAL CANCER METASTATIC COLORECTAL CANCER STAGE IV COLORECTAL CANCER, GENETICS OF

Blood test may spot hidden cancer after abdominal surgery

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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