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Meal-Time blood pressure dips linked to anesthesia risks in elderly?

NCT ID NCT05575661

NEW Knowledge-focused Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

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Recruiting now
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Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers at Peking Union Medical College Hospital are observing 121 older adults scheduled for non-cardiac surgery under general anesthesia. They want to see whether a drop in blood pressure after eating is related to a sudden drop in blood pressure during anesthesia induction. The study tracks blood pressure before and during surgery to understand if one predicts the other.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, doctors could check blood pressure after meals before surgery and adjust anesthesia plans to prevent dangerous drops during operations.
What could go wrong
This is an observational study, so it can only show a pattern, not prove cause and effect. The findings may not apply to all elderly patients or all types of surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

121 people

The number who actually took part.

Started

Nov 2022

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Elderly patients scheduled for elective non-cardiac surgery under general anesthesia in Peking Union Medical College Hospital

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Elderly patients (≥ 65 years old）; 2. Patients with American Society of Anesthesiologists(ASA) grade I-III; 3. Patients scheduled to undergo elective non-cardiac surgery under general anesthesia, with an anticipated surgical duration of over 1 hour； 4. Patients with intra-tracheal intubation following intravenous general ；anesthesia induction and maintenance； Exclusion Criteria: 1. Patients with vascular diseases such as aortic aneurysm, aortic dissection, symptomatic atherosclerotic obliterans, Buerger's disease, and Raynaud's syndrome 2. Patients with secondary hypertension, including renal hypertension and endocrine hypertension. 3. Patients with chronic kidney disease requiring dietary restrictions or dialysis. 4. Patients with Parkinson's disease or other conditions causing tremors. 5. Patients with problems related to oral food ingestion or those requiring enteral nutrition. 6. Patients with difficulties in measuring the upper extremities or communication problems that would interfere with study procedures. 7. Patients unable to remain in a supine position for at least 2 hours.

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Conditions

The condition(s) this trial relates to.

postprandial hypotension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-induction hypotension Postprandial hypotension

Contacts and locations

Locations

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

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