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Can a Blood-Pressure reading predict dangerous drops during heart surgery?

NCT ID NCT07831252

NEW Knowledge-focused Sponsor: Haseki Training and Research Hospital Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers at a Turkish hospital are studying 40 adults scheduled for open-heart surgery to see whether a hemodynamic measure called dynamic arterial elastance (Eadyn) can predict low blood pressure during anesthesia induction. Patients are monitored from one minute before anesthesia to ten minutes after, and are grouped by whether their blood pressure drops. The team records invasive heart and blood-vessel measurements, plus oxygen levels in the brain and kidneys, to understand how blood pressure relates to tissue oxygenation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the monitor proves useful, doctors could one day spot which heart-surgery patients are likely to drop their blood pressure during anesthesia and act sooner to protect organs.
What could go wrong
This is a small observational study of 40 people, so it can only show a pattern, not prove cause and effect. The findings may not apply to patients with arrhythmias, severe heart failure, or other conditions excluded from the study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with coronary artery disease who were scheduled to undergo elective open-heart surgery were included in the study.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: • American Society of Anaesthesiologists (ASA) Physical Status classification I to III • Patients who planned open heart surgery Exclusion Criteria: • Age \< 18 years * Presence of arrhythmia (atrial fibrillation or frequent premature beats) * Severe valvular heart disease (aortic or mitral stenosis/insufficiency) * Severe heart failure (EF \< 40%) * Congenital heart disease * Severe chronic lung disease * Chronic kidney disease requiring dialysis * Severe peripheral vascular disease * Morbid obesity * Emergency surgery cases

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral and kidney regional saturation EADYN Open heart surgery Post-induction hypotension

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Haseki Educational and Research Hospital

    RECRUITING

    Istanbul, Sultangazi, 34270, Turkey (Türkiye)

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