Blood cell harvest could fuel future immune disease cures

NCT ID NCT00001405

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 14 times

Summary

This study collects blood stem cells and immune cells from healthy volunteers and patients with primary immune deficiencies or blood disorders. The cells are used in the lab to develop new gene and cell therapies. Up to 850 adults aged 18-70 will participate. The goal is to advance treatments, not to directly treat participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Blood stem cells and immune cells collected via apheresis or bone marrow harvest
What this could lead to: If successful, this could help create new gene therapies or cell treatments for people with inherited immune disorders.
What could go wrong: This is a collection study, not a treatment trial. The cells are used for lab research or other approved protocols, so direct benefits to participants are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic granulomatous disease Granuloma hematologic disorder hereditary disease inborn error of immunity Infections leukocyte disorder X-linked disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENETIC DISEASE, INBORN GENETIC DISEASE, X-LINKED GRANULOMA GRANULOMATOUS DISEASE, CHRONIC LEUKOCYTE DISEASE

Contacts and locations

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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