New transplant approach aims to cut Graft-Versus-Host disease in blood cancer patients

This early-phase study tests a new way to do stem cell transplants for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors will give patients specially prepared immune cells (regulatory T-cells) along with regular donor cells. The goal is to see if this approach can reduce the risk of graft-versus-host disease and improve survival without relapse. About 66 participants will receive a reduced-intensity transplant followed by these cell infusions.