Blood test may predict lung decline in rare disease

NCT ID NCT04844359

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking for markers in the blood that can predict whether a person's chronic hypersensitivity pneumonitis will get worse over time. Researchers will follow about 137 patients at 7 U.S. centers for 24 months, tracking lung function, symptoms, and CT scans. The goal is to develop a tool that helps doctors personalize care, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that helps doctors predict which patients with chronic hypersensitivity pneumonitis will get worse, allowing for earlier and more personalized treatment.

What could go wrong

This is an observational study, not a treatment trial. It is relatively small (137 people) and only looks for patterns in the blood. The findings may not apply to all patients or lead to immediate changes in care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypersensitivity pneumonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • University of Arizona

    Tucson, Arizona, 85719, United States

  • University of California Davis

    Sacramento, California, 95817, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Texas Southwestern

    Dallas, Texas, 75390, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States