New hope for bladder cancer: chemo, immunotherapy, and radiation may save the bladder

NCT ID NCT05975307

First seen Dec 12, 2025 · Last updated May 10, 2026 · Updated 16 times

Summary

This study tests a treatment plan for muscle-invasive bladder cancer that aims to avoid bladder removal. About 71 participants will receive chemotherapy and an immunotherapy drug (toripalimab) before radiation therapy, plus more immunotherapy during radiation. The goal is to see if this combination can eliminate the cancer while keeping the bladder intact.

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Contacts and locations

Locations

  • Cancer Center, Sun Yat-sen University

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.