New study aims to sharpen bipolar diagnosis and treatment for youth

NCT ID NCT05427123

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study follows 80 youth aged 9 to 19 with bipolar disorder across four U.S. sites. Researchers will track mood symptoms, inflammation, and family conflict over 12 months to find what predicts better or worse outcomes. The goal is to create standardized tools and best-practice guidelines for diagnosing and treating bipolar disorder in young people.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better guidelines for diagnosing and treating bipolar disorder in young people.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove what treatments work best. Results may not apply to all youth with bipolar disorder.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, Los Angeles, Max Gray Child and Adolescent Mood Disorders Program (CHAMP)

    RECRUITING

    Los Angeles, California, 90024, United States

  • University of Colorado Anschutz Medical Campus, Helen and Arthur E. Johnson Depression Center

    ENROLLING_BY_INVITATION

    Aurora, Colorado, 80045, United States

  • University of Pittsburgh Child and Adolescent Bipolar Spectrum Services Clinic (CABS)

    ENROLLING_BY_INVITATION

    Pittsburgh, Pennsylvania, 15213, United States

  • Virginia Commonwealth University Medical Center

    ENROLLING_BY_INVITATION

    Richmond, Virginia, 23298, United States

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