Scientists hunt for blood clues to bipolar disorder
NCT ID NCT07434414
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study looked at two specific proteins in the blood of people with bipolar disorder during a manic episode and compared them to healthy volunteers. The goal was to see if these proteins, which are linked to inflammation and brain cell communication, could help explain the condition. 72 people took part, and the researchers measured their blood and mood symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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72 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Jan 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consisted of adult participants aged 18-65 years. The bipolar disorder (BD) group included consecutive patients diagnosed with BD according to DSM-5-TR criteria who were admitted to the psychiatry clinic of Elazığ Mental Health and Diseases Hospital (Turkey). The healthy control (HC) group consisted of individuals from the general population who applied to the hospital medical board and had no current or past psychiatric or significant medical disorders. All participants provided informed consent prior to enrollment.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1. For Bipolar Disorder (BD) Group: \*Inclusion Criteria: * Diagnosis of BD according to DSM-5-TR * Acute manic episode * Medication-free for at least one month prior to admission * Age ≥ 18 years and \<65 years * Provided informed consent For Bipolar Disorder (BD) Group: \* Exclusion Criteria: • Hypertension • Diabetes mellitus • Chronic kidney disease • Rheumatoid arthritis • Systemic lupus erythematosus • Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than BD * Alcohol/drug/substance use 2. For Healthy Control Group: \*Inclusion Criteria: • No psychiatric diagnosis • No systemic or immunological illness * Medication-free for at least one month * Age ≥ 18 years and \< 65 years * Provided informed consent For Healthy Control Group: \*Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Having psychiatric disorders * Alcohol/drug/substance use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Elazığ Mental Health and Diseases Hospital Psychiatry Clinic
Elâzığ, Elâzığ, 23200, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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