Virus injection takes on Hard-to-Treat cancers in early trial
NCT ID NCT06215846
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a single injection of a modified virus (BioTTT001) directly into tumors in 12 adults with advanced solid cancers that have not responded to standard treatments. The virus is designed to infect and kill cancer cells while also boosting the immune system. The main goals are to check safety, find the best dose, and see how the virus behaves in the body.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BioTTT001 (a modified virus that targets cancer cells and delivers an immune-boosting protein)
- What this could lead to
- If it works, this could point toward a new way to treat advanced solid tumors by using a virus to attack cancer cells and stimulate the immune system.
- What could go wrong
- This is a very early Phase 1 trial with only 12 people, so it is mainly checking safety and dosing. The virus may not shrink tumors or could cause side effects like flu-like symptoms or inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MALIGNANT SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of China Medical Univeristy
Shenyang, Liaoning, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shield nerves from Chemotherapy's side effects?
- Can a Tumor's DNA guide better cancer care for kids?
- Ear acupressure: a new weapon against chemotherapy side effects?
- Can a new PET tracer reveal a key cancer target?
- Can a smart drug home in on Hard-to-Treat cancers?
- Can a new tracer light up cancer growth?