Virus injection takes on Hard-to-Treat cancers in early trial

NCT ID NCT06215846

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a single injection of a modified virus (BioTTT001) directly into tumors in 12 adults with advanced solid cancers that have not responded to standard treatments. The virus is designed to infect and kill cancer cells while also boosting the immune system. The main goals are to check safety, find the best dose, and see how the virus behaves in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BioTTT001 (a modified virus that targets cancer cells and delivers an immune-boosting protein)

What this could lead to

If it works, this could point toward a new way to treat advanced solid tumors by using a virus to attack cancer cells and stimulate the immune system.

What could go wrong

This is a very early Phase 1 trial with only 12 people, so it is mainly checking safety and dosing. The virus may not shrink tumors or could cause side effects like flu-like symptoms or inflammation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenoviridae infectious disease cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of China Medical Univeristy

    Shenyang, Liaoning, China