Blood test could predict brain inflammation relapses in kids

NCT ID NCT06863974

Recruiting now Knowledge-focused Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find blood-based biomarkers that can predict whether a child with acute disseminated encephalomyelitis (ADEM) will experience relapses. Researchers will analyze immune cells from blood samples of 20 children aged 1-18 with a first demyelinating event. The goal is to identify molecular or cellular signatures that indicate a higher risk of recurrence, enabling earlier use of disease-modifying therapies to prevent long-term disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which children with ADEM will have relapses, allowing earlier treatment to prevent long-term damage.
What could go wrong: This is a small, early observational study with only 20 participants, so findings may not apply to all patients. It looks for patterns in blood, not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE DISSEMINATED ENCEPHALOMYELITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute disseminated encephalomyelitis autoimmune disorder of the nervous system autoimmune encephalitis myelin oligodendrocyte glycoprotein antibody-associated disease myelitis optic neuritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DISSEMINATED ENCEPHALOMYELITIS ENCEPHALITIS AUTOIMMUNE

Contacts and locations

Locations

CHU Montpellier
NOT_YET_RECRUITING

Montpellier, 34295, France
CHU d'Angers
RECRUITING

Angers, 49240, France
Hôpital Necker Enfants Malades
NOT_YET_RECRUITING

Paris, 75015, France
Univesity Hostipal of APHP
RECRUITING

Le Kremlin-Bicêtre, 94270, France
Univesity Hostipal of Brest
RECRUITING

Brest, 29200, France
Univesity Hostipal of Nantes
RECRUITING

Nantes, 44093, France
Univesity Hostipal of Rennes
RECRUITING

Rennes, 35000, France
Univesity Hostipal of Tours
RECRUITING

Tours, 37000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.