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Could a peptide supplement supercharge muscle gains from weightlifting?

NCT ID NCT07773142

Disease control Sponsor: University of Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 21, 2026 · Updated 2 times

Summary

This trial tests whether taking a daily bioactive peptide supplement alongside a structured 8-week resistance exercise program leads to greater muscle growth and strength than exercise with a placebo. Healthy young adults aged 18-35 who are not currently weight training will participate. Researchers will measure muscle size, strength, and underlying cellular processes using muscle samples taken before and after the training period.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A daily bioactive peptide supplement combined with resistance exercise training
What this could lead to
If it works, this could point toward a supplement that enhances muscle growth and strength more than exercise alone, potentially benefiting athletes and those seeking to improve metabolic health.
What could go wrong
This is a small, early-stage trial in healthy young adults, so results may not apply to other groups. The supplement may not produce meaningful gains beyond standard training, and muscle biopsies carry minor risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18-35 years * Body Mass Index (BMI, calculated by research team based on height and weight) between 18.5-27.4 kg.m-2 * Meeting UK physical activity guidelines (150 mins moderate or 75 mins vigorous activity/week) * Not currently participating in structured progressive resistance exercise training or have regularly participated in previous 6 months * In good health, being free from disease or conditions (e.g., Type-II diabetes, hyper/hypothyroidism, irritable bowel syndrome, polycystic ovary syndrome) which influence skeletal muscle metabolism or digestion (self-declared) Exclusion Criteria: * Have an allergy to ingredients of the supplement or placebo supplement (e.g., legume/bean, corn allergies) * Have used dietary supplements which are known to affect skeletal muscle recovery and exercise adaptations (e.g., creatine) within the previous month * Are a smoker/vaper or have a history of smoking/vaping in previous year * Have a respiratory condition (e.g., asthma, chronic obstructive pulmonary disease) * Using hormone therapy (not including birth control), anabolic steroids, or recreational drugs * Are pregnant or currently breastfeeding * Are currently trying to conceive a child * Have any injury or body weakness which prevents participation in full body resistance exercise * Have a known allergy to lidocaine

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Conditions

The condition(s) this trial relates to.

Hypertrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dietary supplements to promote muscle growth Resistance training adaptation Supplement

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham

    RECRUITING

    Birmingham, Birmingham, B15 2TT, United Kingdom

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