One set or many? study tests best way to build muscle in sedentary men

NCT ID NCT07337304

Completed Knowledge-focused Sponsor: Inonu University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared doing one set versus multiple sets of resistance exercises in 34 sedentary men aged 18-40. Participants were randomly assigned to a single-set group, a multiple-set group, or a no-exercise control group. Researchers measured changes in muscle strength, size, and power after a structured training program. The goal was to find the optimal training volume for beginners.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Resistance training (structured exercise program using free weights and machines)
What this could lead to: If successful, this study could help determine the most effective number of exercise sets for building strength and muscle in people new to training.
What could go wrong: This is a small, completed study with only 34 participants. Results may not apply to women, older adults, or trained individuals. No long-term follow-up was done.

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROMUSCULAR ADAPTATIONS RESISTANCE TRAINING ADAPTATION SEDENTARY LIFESTYLE

Contacts and locations

Locations

Inonu University, Faculty of Sport Sciences

Malatya, 44280, Turkey (Türkiye)

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