Could bile acids explain why kids with colitis get more c. diff infections?
NCT ID NCT06228352
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at bile acid profiles in children with ulcerative colitis (UC) who also have a C. difficile infection. Researchers want to see if changes in bile acids and gut bacteria make these children more vulnerable. They will compare three groups: children with UC flare-ups with or without C. diff, those in remission, and healthy kids. No treatments are given—just stool samples are collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could reveal why children with ulcerative colitis are more prone to C. difficile infections, pointing toward future preventive strategies.
- What could go wrong
- This is an observational study with only 80 participants, so findings may not apply broadly. It does not test any treatment, so direct patient benefits are not expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Necker-Enfants Malades
RECRUITINGParis, 75015, France
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