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Could a prostate cancer drug help women with fatty liver and PCOS?

NCT ID NCT05979389

Recruiting now Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests whether bicalutamide, a drug that blocks male hormones, can improve liver health in women aged 18-42 who have both polycystic ovary syndrome (PCOS) and nonalcoholic fatty liver disease (NAFLD). About 50 participants will receive either bicalutamide or a placebo for a short time. The goal is to see if reducing androgen activity can lower liver fat and stiffness, which may help prevent serious liver damage.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NAFLD PCOS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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Other studies related to the condition(s) this trial covers.