New chemo cocktail shows promise for tough-to-treat colorectal cancer
NCT ID NCT04230187
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a more intense chemotherapy regimen (mFOLFOXIRI) plus the drug bevacizumab against a standard regimen (mFOLFOX-6) plus bevacizumab as a first treatment for people with advanced colorectal cancer that cannot be removed by surgery. The trial includes 528 participants in China and measures how long the cancer stays under control, tumor shrinkage, and side effects. The goal is to find a more effective option for Asian patients who often have trouble tolerating standard high-dose treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Gastrointestinal Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510655, China