Blood tests may guide breast cancer treatment before surgery
NCT ID NCT07610525
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing whether blood tests and imaging scans can tell if chemotherapy is working in people with early-stage triple-negative breast cancer before they go to surgery. The study will enroll 200 participants who will receive a combination of chemotherapy drugs (paclitaxel and carboplatin) plus the immunotherapy drug pembrolizumab. The goal is to see if these tests can identify who has already had a complete response, potentially allowing for more personalized treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Paclitaxel, Carboplatin, Pembrolizumab
- What this could lead to
- If successful, this could help doctors personalize treatment for early-stage triple-negative breast cancer, potentially avoiding unnecessary surgery or adjusting therapy earlier.
- What could go wrong
- This is an early phase 2 trial with only 200 participants, so results may not apply to everyone. The tests being studied might not accurately predict response, and the combination chemotherapy plus immunotherapy has known side effects like fatigue, nausea, and immune-related reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
MD Anderson Cancer Center
Houston, Texas, 77030, United States
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