New bowel prep could boost colonoscopy success in cirrhosis patients

NCT ID NCT07668778

Not yet recruiting Disease control Sponsor: Hospital do Divino Espírito Santo de Ponta Delgada Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a laxative (bisacodyl) and a longer low-fiber diet to the standard bowel prep improves colonoscopy quality in people with cirrhosis. About 252 adults will be randomly assigned to either the standard or modified prep. The goal is to see if the new approach leads to better colon cleaning and higher detection of polyps or cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: polyethylene glycol (PEG) plus bisacodyl
What this could lead to: If it works, this could provide a safer, more effective bowel preparation method for people with cirrhosis, improving colonoscopy quality and colorectal cancer detection.
What could go wrong: This is a Phase 3 trial, but it hasn't started recruiting yet. The modified regimen may not significantly improve outcomes and could cause more side effects like cramping or dehydration.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BOWEL PREPARATION CIRRHOSIS

Contacts and locations

Locations

Hospital Central do Funchal, SESARAM

Funchal, Madeira, 9004-514, Portugal
Hospital do Divino Espírito Santo de Ponta Delgada

Ponta Delgada, São Miguel, 9500-370, Portugal
ULS da Arrábida

Setúbal, 2910-446, Portugal
ULS de Coimbra

Coimbra, 3004-561, Portugal

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