New bowel prep could boost colonoscopy success in cirrhosis patients

NCT ID NCT07668778

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a laxative (bisacodyl) and a longer low-fiber diet to the standard bowel prep improves colonoscopy quality in people with cirrhosis. About 252 adults will be randomly assigned to either the standard or modified prep. The goal is to see if the new approach leads to better colon cleaning and higher detection of polyps or cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

polyethylene glycol (PEG) plus bisacodyl

What this could lead to

If it works, this could provide a safer, more effective bowel preparation method for people with cirrhosis, improving colonoscopy quality and colorectal cancer detection.

What could go wrong

This is a Phase 3 trial, but it hasn't started recruiting yet. The modified regimen may not significantly improve outcomes and could cause more side effects like cramping or dehydration.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Central do Funchal, SESARAM

    Funchal, Madeira, 9004-514, Portugal

  • Hospital do Divino Espírito Santo de Ponta Delgada

    Ponta Delgada, São Miguel, 9500-370, Portugal

    Contact Email: •••••@•••••

  • ULS da Arrábida

    Setúbal, 2910-446, Portugal

  • ULS de Coimbra

    Coimbra, 3004-561, Portugal