New drug cocktail aims to shrink Hard-to-Treat tumors
NCT ID NCT05372640
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 34 times
Summary
This early-phase trial tests two drugs—ZEN003694 and abemaciclib—together in people with advanced NUT carcinoma, breast cancer, or other solid tumors that have spread or can't be removed. The main goals are to find the safest dose and see if the combination can shrink or stabilize the cancer. About 45 participants will take part to help determine next steps.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact Phone: •••-•••-••••
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Keck Medicine of USC Koreatown
RECRUITINGLos Angeles, California, 90020, United States
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Contact Phone: •••-•••-••••
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Los Angeles General Medical Center
RECRUITINGLos Angeles, California, 90033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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USC / Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact
Contact Phone: •••-•••-••••
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USC Norris Oncology/Hematology-Newport Beach
RECRUITINGNewport Beach, California, 92663, United States
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Contact Phone: •••-•••-••••
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
Contact
Contact Phone: •••-•••-••••
Conditions
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