Can less radiation be better for brain cancer patients?
NCT ID NCT06719440
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 32 times
Summary
The BELGICA trial is testing whether a smaller radiation target in glioblastoma patients can reduce side effects and improve quality of life without shortening survival. About 347 adults with newly diagnosed glioblastoma will be randomly assigned to standard or reduced radiation volume. The study aims to find a safer way to deliver radiotherapy.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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AZ Delta
RECRUITINGRoeselare, 8800, Belgium
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AZ Groeninge
RECRUITINGKortrijk, 8500, Belgium
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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AZ Sint Jan
RECRUITINGBruges, 8000, Belgium
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AZ Sint Maarten
RECRUITINGMechelen, 2800, Belgium
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AZ Sint-Lucas
RECRUITINGGhent, 9000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CH Mouscron
NOT_YET_RECRUITINGMouscron, 7700, Belgium
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CHR Verviers
RECRUITINGVerviers, 4800, Belgium
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CHU Liège
RECRUITINGLiège, 4000, Belgium
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU UCL Namur - Sainte Elisabeth
RECRUITINGNamur, 5000, Belgium
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Chu Helora
RECRUITINGLa Louvière, 7100, Belgium
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Cliniques de l'Europe
RECRUITINGUccle, 1180, Belgium
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Cliniques universitaires Saint-Luc
RECRUITINGBrussels, 1200, Belgium
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EpiCURA
RECRUITINGBaudour, 7331, Belgium
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Grand Hôpital de Charleroi
RECRUITINGGilly, 6060, Belgium
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Hôpital André Vésale - HUmani
RECRUITINGMontigny-le-Tilleul, 6110, Belgium
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Institut Jules Bordet
NOT_YET_RECRUITINGBrussels, 1070, Belgium
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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JESSA Ziekenhuis
RECRUITINGHasselt, 3500, Belgium
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Olv Azorg
NOT_YET_RECRUITINGAalst, 9300, Belgium
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Brussel
NOT_YET_RECRUITINGBrussels, 1090, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Gent
NOT_YET_RECRUITINGGhent, 9000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Leuven
RECRUITINGLeuven, 3000, Belgium
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ZAS Augustinus
RECRUITINGWilrijk, 2610, Belgium
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ziekenhuis Oost-Limburg (ZOL)
RECRUITINGGenk, 3600, Belgium
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Radiotherapy
What this could lead to
If successful, this could lead to a safer radiotherapy approach for glioblastoma, reducing brain side effects and improving quality of life while maintaining survival.
What could go wrong
This is a Phase NA trial with 347 participants. The smaller radiation field might miss microscopic tumor cells, potentially reducing survival. Results are not yet available.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.