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Could shrinking radiation targets improve life for brain cancer patients?

NCT ID NCT06719440

Recruiting now Disease control Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The BELGICA trial is testing whether giving radiation in a more focused way to people with glioblastoma can reduce side effects and improve quality of life without shortening survival. About 347 newly diagnosed patients will be randomly assigned to receive either standard or reduced radiation margins around the tumor. The study aims to find a safer way to deliver radiotherapy while maintaining its effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiotherapy
What this could lead to
If successful, this could lead to a new standard of care that reduces brain radiation side effects and improves quality of life for glioblastoma patients.
What could go wrong
This is a Phase NA trial with 347 participants. The smaller radiation field might not control the tumor as well, potentially reducing survival. Results are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioblastoma radiation injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA RADIOTHERAPY SIDE EFFECT

Contacts and locations

Locations

  • AZ Delta

    RECRUITING

    Roeselare, 8800, Belgium

  • AZ Groeninge

    RECRUITING

    Kortrijk, 8500, Belgium

  • AZ Sint Jan

    RECRUITING

    Bruges, 8000, Belgium

  • AZ Sint Maarten

    RECRUITING

    Mechelen, 2800, Belgium

  • AZ Sint-Lucas

    RECRUITING

    Ghent, 9000, Belgium

  • CH Mouscron

    NOT_YET_RECRUITING

    Mouscron, 7700, Belgium

  • CHR Verviers

    RECRUITING

    Verviers, 4800, Belgium

  • CHU Liège

    RECRUITING

    Liège, 4000, Belgium

  • CHU UCL Namur - Sainte Elisabeth

    RECRUITING

    Namur, 5000, Belgium

  • Chu Helora

    RECRUITING

    La Louvière, 7100, Belgium

  • Cliniques de l'Europe

    RECRUITING

    Uccle, 1180, Belgium

  • Cliniques universitaires Saint-Luc

    RECRUITING

    Brussels, 1200, Belgium

  • EpiCURA

    RECRUITING

    Baudour, 7331, Belgium

  • Grand Hôpital de Charleroi

    RECRUITING

    Gilly, 6060, Belgium

  • Hôpital André Vésale - HUmani

    RECRUITING

    Montigny-le-Tilleul, 6110, Belgium

  • Institut Jules Bordet

    NOT_YET_RECRUITING

    Brussels, 1070, Belgium

  • JESSA Ziekenhuis

    RECRUITING

    Hasselt, 3500, Belgium

  • Olv Azorg

    NOT_YET_RECRUITING

    Aalst, 9300, Belgium

  • UZ Brussel

    NOT_YET_RECRUITING

    Brussels, 1090, Belgium

  • UZ Gent

    NOT_YET_RECRUITING

    Ghent, 9000, Belgium

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

  • ZAS Augustinus

    RECRUITING

    Wilrijk, 2610, Belgium

  • Ziekenhuis Oost-Limburg (ZOL)

    RECRUITING

    Genk, 3600, Belgium

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