New combo therapy shows promise for stubborn depression
NCT ID NCT06431386
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times
Summary
This study tested whether adding a type of talk therapy (behavioral activation) to esketamine treatment helps people with depression that hasn't improved with standard medications. Six adults with major depression or bipolar disorder took part. The goal was to see if practicing new behaviors while esketamine improved their mood could lead to longer-lasting relief from depressive symptoms.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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The Royal Ottawa Mental Health Centre
Ottawa, Ontario, K1Z 7K4, Canada
Conditions
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