Could a common arthritis pill fight brain diseases?

NCT ID NCT05189106

Summary

This early-stage study tested whether baricitinib, a drug approved for rheumatoid arthritis, can get into the spinal fluid and reduce signs of brain inflammation in people with Alzheimer's disease, ALS, or early memory concerns. Seventeen participants took the pill daily for 24 weeks. The main goal was to measure drug levels and inflammatory markers in spinal fluid, not to see if it improved symptoms.

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Contacts and locations

Locations

  • Massachusetts General Hospital - AD Site

    Charlestown, Massachusetts, 02129, United States

  • Massachusetts General Hospital - ALS Site

    Boston, Massachusetts, 02129, United States

Conditions

Explore the condition pages connected to this study.