Gastric bypass may alter how the body absorves blood pressure medication

NCT ID NCT03440177

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates how gastric bypass or sleeve gastrectomy changes the way the body processes ramipril, a drug used to treat high blood pressure. Researchers will measure ramipril levels in the blood of 12 patients before and after surgery. The goal is to understand whether weight-loss surgery affects how well this medication works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ramipril
What this could lead to: If successful, this could help doctors adjust blood pressure medication doses for patients who have had bariatric surgery, ensuring the drug works as intended.
What could go wrong: This is a very small study (12 people) that only measures drug levels in the blood, not health outcomes. Results may not apply to other medications or broader patient groups.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

St. Olavs University Hospital
RECRUITING

Trondheim, Norway

Contact

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