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Weight-Loss surgery may change how your medication works

NCT ID NCT03449472

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study looks at how two common weight-loss surgeries — gastric bypass and sleeve gastrectomy — affect the way the body absorbs the medication quetiapine. Quetiapine is a prescription drug used for mental health conditions. Researchers will measure quetiapine levels in the blood before and after surgery in 12 people with severe obesity. The goal is to understand whether surgery changes how much of the drug reaches the bloodstream, which could help doctors adjust doses in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
quetiapine
What this could lead to
If successful, this study could help doctors adjust quetiapine doses for patients who have had weight-loss surgery, ensuring the medication works as intended.
What could go wrong
This is a small, early-stage study with only 12 participants, so results may not apply to everyone. The findings will show how surgery affects drug levels, but not whether those changes are clinically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

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