Gastric bypass may change how your body absorbs painkillers

NCT ID NCT03476577

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates how gastric bypass and sleeve gastrectomy—two common weight-loss surgeries—alter the way the body processes ibuprofen. Researchers will measure ibuprofen levels in the blood of 12 participants before and after surgery. The goal is to understand whether these procedures change drug absorption, which could affect pain relief and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ibuprofen
What this could lead to: If successful, this could help doctors adjust ibuprofen doses for people who have had weight-loss surgery, ensuring the drug works as intended.
What could go wrong: This is a small, early-stage study with only 12 participants, so results may not apply to everyone. It only looks at one drug, not all medications.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

St. Olavs University Hospital
RECRUITING

Trondheim, Norway

Contact

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