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Stomach surgery may change how blood pressure drugs work

NCT ID NCT03460366

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study looks at how gastric bypass and sleeve gastrectomy — two types of weight-loss surgery — change the way the body absorbs enalapril, a common blood pressure medication. Researchers will measure drug levels in the blood of 12 people with severe obesity before and after surgery. The goal is to understand whether surgery alters how much of the drug reaches the bloodstream, which could help doctors prescribe safer, more effective doses after bariatric procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
enalapril
What this could lead to
If successful, this study could help doctors adjust blood pressure medication doses after weight-loss surgery, ensuring patients get the right amount of drug.
What could go wrong
This is a very small study (12 people) that only measures drug levels, not health outcomes. Results may not apply to other medications or all surgery types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

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