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Stomach surgery may change how antipsychotics work

NCT ID NCT03449485

Recruiting now Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study looks at how gastric bypass or sleeve gastrectomy changes the way the body processes the antipsychotic medication chlorprothixene. Researchers will measure drug levels in the blood of 12 people with severe obesity before and after surgery. The goal is to understand whether weight-loss surgery alters drug absorption, which could help doctors prescribe safer, more effective doses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Chlorprothixene
What this could lead to
If successful, this could help doctors adjust medication doses after bariatric surgery to ensure patients get the right amount of drug.
What could go wrong
This is a very small, early-stage study with only 12 participants, so results may not apply to everyone. It measures drug levels, not health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

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