Gastric bypass may alter how blood pressure meds work

NCT ID NCT03460327

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates how bariatric surgery (gastric bypass or sleeve gastrectomy) changes the way the body absorbs candesartan, a drug used to treat high blood pressure. Researchers will measure candesartan levels in the blood of 12 people with severe obesity before and after surgery. The goal is to understand whether these common weight-loss procedures affect how well the medication works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
candesartan
What this could lead to
If this study finds that bariatric surgery changes how candesartan is absorbed, it could help doctors adjust doses for patients after surgery.
What could go wrong
This is a very small study (12 people) that only measures drug levels in the blood, not health outcomes. Results may not apply to other medications or populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

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