Gastric bypass may alter how blood thinners work

NCT ID NCT03448783

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates how two common weight-loss surgeries—gastric bypass and sleeve gastrectomy—change the way the body absorbs the blood thinner apixaban. Researchers will measure apixaban levels in the blood of 12 participants before and after surgery. The goal is to understand whether these surgeries affect drug availability, which could help guide safer dosing in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
apixaban
What this could lead to
If successful, this study could help doctors adjust blood thinner doses for people who have had weight-loss surgery, improving safety and effectiveness.
What could go wrong
This is a very small study (12 people) that only measures drug levels, not clinical outcomes. Results may not apply to all patients or other medications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

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