Weight-loss surgery may alter how blood pressure drugs work in the body

NCT ID NCT03497156

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study looks at how bariatric surgery (gastric bypass or sleeve gastrectomy) affects the levels of the blood pressure drug lercanidipine in the blood. Researchers will measure drug concentrations before and after surgery in 12 people with severe obesity. The goal is to understand whether surgery changes how the body absorbs and processes this medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lercanidipine
What this could lead to
If it works, this could help doctors adjust medication doses for people who have had bariatric surgery, ensuring they get the right amount of drug.
What could go wrong
This is a very small, early study (12 people) that only measures drug levels, not health outcomes. Results may not apply to other drugs or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Olavs University Hospital

    RECRUITING

    Trondheim, Norway

    Contact

More trials for these conditions

Other studies related to the condition(s) this trial covers.