Could less lymph node surgery be better for High-Risk prostate cancer?
NCT ID NCT07580196
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at men with high-risk prostate cancer that appears on only one side of the prostate. During robotic surgery to remove the prostate, doctors will either remove lymph nodes from both sides of the pelvis or just the side with cancer. The goal is to see if removing fewer lymph nodes reduces side effects and recovery time without raising the risk of cancer coming back. About 820 men will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AOU Città della Salute e della Scienza di Torino, Ospedale Molinette
RECRUITINGTorino, 10126, Italy
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ASST Grande Ospedale Metropolitano Niguarda
NOT_YET_RECRUITINGMilan, 20162, Italy
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Humanitas Clinical and Research Centre & Humanitas University
NOT_YET_RECRUITINGRozzano, Milano, 20089, Italy
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IEO, Istituto Europeo di Oncologia
NOT_YET_RECRUITINGMilan, 20141, Italy
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IFO - Istituti Fisioterapici Ospitalieri
NOT_YET_RECRUITINGRoma, 00144, Italy
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IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola-Malpighi & University of Bologna
NOT_YET_RECRUITINGBologna, 40138, Italy
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IRCCS Ospedale Policlinico San Martino & University of Genoa
NOT_YET_RECRUITINGGenova, 16132, Italy
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Istituto Nazionale Tumori, IRCCS, Fondazione "G. Pascale"
NOT_YET_RECRUITINGNaples, 80131, Italy
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Policlinico Universitario Gemelli IRCCS & Università Cattolica del Sacro Cuore
NOT_YET_RECRUITINGRoma, 00168, Italy
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Università Tor Vergata / Policlinico Tor Vergata
NOT_YET_RECRUITINGRoma, 00133, Italy
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Università degli Studi di Firenze / AOU Careggi
NOT_YET_RECRUITINGFlorence, 50134, Italy
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Università degli Studi di Foggia / AO Ospedali Riuniti di Foggia
NOT_YET_RECRUITINGFoggia, 71122, Italy
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Università degli Studi di Modena / AOU Modena
NOT_YET_RECRUITINGModena, 41124, Italy
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Università degli Studi di Verona / AOU Verona
NOT_YET_RECRUITINGVerona, 37134, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new tracer light up hidden prostate cancer?
- Could deep breaths before surgery ward off Post-Op confusion?
- A second look: MRI screening may spot hidden prostate cancers
- Can precision protons spare the bowel in prostate cancer?
- AI coaches doctors on cancer risk talks
- Can an immune booster make hormone therapy work better against prostate cancer?