New drug combo targets tough cancers in early trial

NCT ID NCT05797168

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 04, 2026 · Updated 31 times

Summary

This study tests an experimental drug called AZD5335, alone or with other cancer treatments, in people with advanced ovarian, lung, or endometrial cancers that have not responded to standard therapy. The main goals are to check safety and find the right dose. About 506 participants will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
RECRUITING

Duarte, California, 91010, United States
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Irvine, California, 92618, United States
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WITHDRAWN

La Jolla, California, 92093, United States
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Aurora, Colorado, 80045, United States
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TERMINATED

Louisville, Kentucky, 40202, United States
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Boston, Massachusetts, 02114, United States
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Detroit, Michigan, 48201, United States
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Columbus, Ohio, 43201, United States
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Portland, Oregon, 97239, United States
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Providence, Rhode Island, 02903, United States
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Providence, Rhode Island, 02905, United States
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Houston, Texas, 77030, United States
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Fairfax, Virginia, 22031, United States
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Liverpool, 2170, Australia
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Melbourne, 3000, Australia
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Edmonton, Alberta, T6G 1Z2, Canada
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London, Ontario, N6A 5W9, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Montreal, Quebec, H2X 0A9, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Chengdu, 610041, China
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Chongqing, 400030, China
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Guangzhou, 510000, China
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Guangzhou, 510060, China
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Jinan, 250117, China
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Xi'an, 710061, China
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Zhengzhou, 450008, China
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NOT_YET_RECRUITING

Berlin, 13353, Germany
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NOT_YET_RECRUITING

Essen, 45136, Germany
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NOT_YET_RECRUITING

Freiburg im Breisgau, 79106, Germany
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Hanover, 30625, Germany
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Leipzig, 04103, Germany
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Mannheim, 68167, Germany
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Regensburg, 93053, Germany
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Haifa, 3109601, Israel
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Ramat Gan, 52621, Israel
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Hidaka-shi, 350-1298, Japan
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Kashiwa, 227-8577, Japan
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Kōtoku, 135-8550, Japan
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Sunto-gun, 411-8777, Japan
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Tokyo, 104-0045, Japan
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Barcelona, 8035, Spain
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Madrid, 28041, Spain
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Madrid, 28050, Spain
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Málaga, 29010, Spain
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 11259, Taiwan
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Ankara, 06050, Turkey (Türkiye)
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Ankara, 06200, Turkey (Türkiye)
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Ankara, 06800, Turkey (Türkiye)
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Istanbul, 34718, Turkey (Türkiye)
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Cambridge, CB2 0XY, United Kingdom
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RECRUITING

Glasgow, Scotland, G12 0YN, United Kingdom
Research Site
NOT_YET_RECRUITING

London, SE1 9RT, United Kingdom
Research Site
RECRUITING

London, SW3 6JJ, United Kingdom
Research Site
RECRUITING

Sutton, SM2 5PT, United Kingdom

Conditions

Explore the condition pages connected to this study.

ENDOMETRIAL CANCER ENDOMETRIAL CANCER LUNG ADENOCARCINOMA OVARIAN CANCER