New drug could protect kidneys during sepsis

NCT ID NCT07215702

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tests an experimental drug called AZD4144 in adults with sepsis who develop acute kidney injury. About 124 people in intensive care will receive either the drug or a placebo daily through an IV. The main goal is to see if the drug helps the kidneys work better compared to placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Tucson, Arizona, 85719, United States
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Newport Beach, California, 92663, United States
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Kansas City, Kansas, 66160, United States
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Baltimore, Maryland, 21211, United States
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Boston, Massachusetts, 02115, United States
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Detroit, Michigan, 48202, United States
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The Bronx, New York, 10451, United States
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The Bronx, New York, 10461, United States
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The Bronx, New York, 10467, United States
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Chapel Hill, North Carolina, 27519, United States
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Winston-Salem, North Carolina, 27157, United States
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Corvallis, Oregon, 97330, United States
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Philadelphia, Pennsylvania, 19140, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Charleston, South Carolina, 29425, United States
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Salt Lake City, Utah, 84107, United States
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CABA, 1430, Argentina
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Ciudad de Buenos Aires, C1180AAX, Argentina
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La Plata, B1900, Argentina
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Rosario, 2000, Argentina
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Brussels, 1200, Belgium
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Genk, 3600, Belgium
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Jette, 1090, Belgium
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Ottignies, 1340, Belgium
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Lévis, Quebec, G6V 3Z1, Canada
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Montreal, Quebec, H1T 2M4, Canada
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Montreal, Quebec, H2X 3E4, Canada
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Montreal, Quebec, H4J 1C5, Canada
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Québec, Quebec, G1R 2J6, Canada
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Brno, 656 91, Czechia
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Kolín, 280 02, Czechia
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Prague, 128 08, Czechia
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Prague, 18000, Czechia
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Aarhus N, 8200, Denmark
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Gistrup, 9260, Denmark
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Hvidovre, 2650, Denmark
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Angers, 49033, France
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La Roche-sur-Yon, 85925, France
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Limoges, 87000, France
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Strasbourg, 67091, Cedex, France
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Tours, 37044, France
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Aachen, 52074, Germany
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Essen, 45147, Germany
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Frankfurt, 60590, Germany
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Greifswald, 17475, Germany
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Heidelberg, 69120, Germany
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SUSPENDED

Kiel, 24105, Germany
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Leipzig, 04103, Germany
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Athens, 11527, Greece
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Thessaloniki, 54642, Greece
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Budapest, 1082, Hungary
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Debrecen, 4032, Hungary
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Kaposvár, 7400, Hungary
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Pécs, 7624, Hungary
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Szeged, 6725, Hungary
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Tatabánya, 2800, Hungary
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Milan, 20122, Italy
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Padua, 35128, Italy
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Roma, 00168, Italy
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Rozzano, 20089, Italy
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Barcelona, 08035, Spain
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Jerez de la Frontera, 11407, Spain
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Valencia, 46026, Spain
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Adapazarı, 54290, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Kahramanmaraş, 46040, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Brighton, BN2 5BE, United Kingdom
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Guildford, GU27XX, United Kingdom
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Liverpool, L7 8XP, United Kingdom
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London, SE1 7EH, United Kingdom

Conditions

Explore the condition pages connected to this study.

ACUTE KIDNEY INJURY SEPSIS