New pill combo aims to crush bad cholesterol
NCT ID NCT07218900
First seen Nov 01, 2025
Summary
This study tests whether adding a new drug called AZD0780 to the common statin rosuvastatin can lower 'bad' LDL cholesterol more than rosuvastatin alone. About 76 adults with high cholesterol will take either AZD0780 or a placebo pill, plus rosuvastatin, for 12 weeks. Neither participants nor doctors know who gets the real drug until the study ends.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DYSLIPIDAEMIA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Research Site
Aramil, 624002, Russia
-
Research Site
Ivanovo, 153012, Russia
-
Research Site
Moscow, 105554, Russia
-
Research Site
Moscow, 111539, Russia
-
Research Site
Moscow, 117292, Russia
-
Research Site
Moscow, 121552, Russia
-
Research Site
Perm, 614000, Russia
-
Research Site
Saint Petersburg, 194156, Russia
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AZD0780 (a small molecule drug taken as a tablet) combined with rosuvastatin (a statin tablet)
What this could lead to
If it works, this could lead to a new combination treatment that lowers 'bad' cholesterol more effectively than statins alone.
What could go wrong
This is an early Phase 2 trial with only 76 people, so results may not apply to everyone. The drug may not lower cholesterol enough or could have side effects not yet seen.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.