Engineered immune cells take on autoimmune diseases in early trial

NCT ID NCT07295847

First seen Dec 24, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This early-phase trial tests a new treatment called AZD0120 for adults with three autoimmune diseases: systemic sclerosis, idiopathic inflammatory myopathies, and difficult-to-treat rheumatoid arthritis. AZD0120 uses a patient's own immune cells that are modified in a lab to target and attack faulty immune cells driving the disease. The main goal is to check safety and find the right dose for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    Tucson, Arizona, 85719, United States

  • Research Site

    NOT_YET_RECRUITING

    Stanford, California, 94305-5847, United States

  • Research Site

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

  • Research Site

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Research Site

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

  • Research Site

    RECRUITING

    New York, New York, 10032, United States

  • Research Site

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • Research Site

    NOT_YET_RECRUITING

    Seattle, Washington, 98104, United States

  • Research Site

    RECRUITING

    Darlinghurst, 2010, Australia

  • Research Site

    NOT_YET_RECRUITING

    Waratah, 2298, Australia

  • Research Site

    NOT_YET_RECRUITING

    Hamburg, 20246, Germany

  • Research Site

    NOT_YET_RECRUITING

    Mainz Am Rhein, 55131, Germany

  • Research Site

    NOT_YET_RECRUITING

    Würzburg, 97080, Germany

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 8035, Spain

  • Research Site

    NOT_YET_RECRUITING

    Madrid, 28041, Spain

  • Research Site

    NOT_YET_RECRUITING

    Madrid, 28046, Spain

  • Research Site

    NOT_YET_RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    London, SE5 9RS, United Kingdom

Conditions

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