Engineered immune cells take aim at autoimmune diseases
NCT ID NCT07295847
First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 4 times
Summary
This early-stage trial tests a new treatment called AZD0120 for adults with three autoimmune diseases: systemic sclerosis, idiopathic inflammatory myopathies, or difficult-to-treat rheumatoid arthritis. AZD0120 is made from a patient's own immune cells, which are modified in a lab to target and attack faulty cells that drive the disease. The main goal is to check the treatment's safety and find the right dose for future studies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Research Site
NOT_YET_RECRUITINGTucson, Arizona, 85719, United States
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NOT_YET_RECRUITINGStanford, California, 94305-5847, United States
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NOT_YET_RECRUITINGChicago, Illinois, 60637, United States
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RECRUITINGAnn Arbor, Michigan, 48109, United States
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NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States
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RECRUITINGNew York, New York, 10032, United States
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NOT_YET_RECRUITINGChapel Hill, North Carolina, 27599, United States
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NOT_YET_RECRUITINGSeattle, Washington, 98104, United States
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RECRUITINGDarlinghurst, 2010, Australia
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NOT_YET_RECRUITINGWaratah, 2298, Australia
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NOT_YET_RECRUITINGBerlin, 13353, Germany
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NOT_YET_RECRUITINGErlangen, 91054, Germany
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NOT_YET_RECRUITINGHamburg, 20246, Germany
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NOT_YET_RECRUITINGJena, 07747, Germany
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NOT_YET_RECRUITINGMainz, 55131, Germany
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NOT_YET_RECRUITINGWürzburg, 97080, Germany
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NOT_YET_RECRUITINGBarcelona, 8035, Spain
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NOT_YET_RECRUITINGMadrid, 28041, Spain
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NOT_YET_RECRUITINGMadrid, 28046, Spain
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NOT_YET_RECRUITINGHuddinge, 141 57, Sweden
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RECRUITINGEdinburgh, EH4 2XU, United Kingdom
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Research Site
NOT_YET_RECRUITINGLondon, SE5 9RS, United Kingdom
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Other studies related to the condition(s) this trial covers.
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