New Gel-Like wrap could stop chronic pain after cancer reconstruction
NCT ID NCT07558096
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether placing a soft tissue matrix over a nerve during forearm flap surgery can prevent chronic pain and numbness. Eighty head and neck cancer patients will be randomly assigned to receive either the matrix or standard closure. The main goal is to see if the matrix reduces neuropathic pain six months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Avive+ soft tissue matrix
What this could lead to
If it works, this could offer a simple way to prevent long-term nerve pain and numbness after reconstructive surgery for head and neck cancer.
What could go wrong
This is a small pilot study (80 people) that hasn't started yet. The matrix may not reduce pain better than standard closure, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
Contact Phone: •••-•••-••••