Wireless pacemaker shows promise for Dual-Chamber pacing

NCT ID NCT05252702

Completed Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new type of pacemaker that doesn't use wires (leads) to help both the upper and lower chambers of the heart beat in sync. It involved 464 people with slow heart rhythms who needed a pacemaker. The main goals were to see if the device was safe and worked well at 3 and 12 months after implantation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aveir DR Leadless Pacemaker System (a device implanted in the heart to regulate heartbeat)
What this could lead to: If successful, this could offer a safer, less invasive option for people needing a dual-chamber pacemaker, potentially reducing complications from traditional pacemakers.
What could go wrong: This was a single study without a comparison group, so results may not apply to everyone. Complications like device-related serious events were tracked, and long-term benefits are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac atrioventricular block Bradycardia cardiac rhythm disease sick sinus syndrome Syncope, Vasovagal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRADYCARDIA CARDIAC PACEMAKER, ARTIFICIAL CARDIAC RHYTHM DISORDER

Contacts and locations

Locations

AdventHealth Orlando

Orlando, Florida, 32803, United States
Amsterdam Academic Medical Centre (AMC)

Amsterdam, 1105 AZ, Netherlands
Arkansas Heart Hospital

Little Rock, Arkansas, 72211, United States
Arrhythmia Research Group

Jonesboro, Arkansas, 72401, United States
Aspirus Wausau Hospital

Wausau, Wisconsin, 54401, United States
Aurora Medical Group

Milwaukee, Wisconsin, 53215, United States
Azienda Ospedaliero Universitaria Pisana

Pisa, 56100, Italy
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Baptist Medical Center

Jacksonville, Florida, 32207, United States
Bryan Heart

Lincoln, Nebraska, 68506, United States
CHRU Albert Michallon

Grenoble, 38043, France
Cardiac Arrhythmia & Pacemaker Center

Roslyn, New York, 11576, United States
Catholic Medical Center

Manchester, New Hampshire, 03102, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Centro Cardiologico Monzino

Milan, 20138, Italy
Charlton Memorial Hospital

Fall River, Massachusetts, 02720, United States
Donald Guthrie Foundation for Education & Research

Sayre, Pennsylvania, 18840, United States
Emory University Hospital

Atlanta, Georgia, 30342, United States
Foothills Medical Centre

Calgary, Alberta, T2N 4N1, Canada
Franciscan Heart & Vascular Associates

Tacoma, Washington, 98405, United States
HSC, Eastern Health

St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Hightower Clinical

Oklahoma City, Oklahoma, 73102, United States
HonorHealth

Scottsdale, Arizona, 85258, United States
Hopital d'adulte de la Timone

Marseille, Alpes, 13005, France
Hospital Clínic de Barcelona

Barcelona, 08036, Spain
Hospital Universitario de Badajoz

Badajoz, Extmdra, 06080, Spain
Huntington Memorial Hospital

Pasadena, California, 91105, United States
Institut de Cardiologie de Montreal (Montreal Heart Inst.)

Montreal, Quebec, Canada
Iowa Heart Center

West Des Moines, Iowa, 50266, United States
Jersey Shore University Medical Center

Ocean City, New Jersey, 07712, United States
John Radcliffe Hospital

Oxford, Soeast, OX3 9DU, United Kingdom
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kepler Universitätsklinikum GmbH

Linz, Upper Austria, 4021, Austria
Kokura Memorial Hospital

Kitakyushu, Fukuoka, Japan
Kurashiki Central Hospital

Kurashiki-shi, Okayama-ken, Japan
Lancaster General Hospital

Lancaster, Pennsylvania, 17602, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Memorial Hermann Hospital

The Woodlands, Texas, 77380, United States
Mount Sinai Hospital

New York, New York, 10029, United States
Naples Heart Rhythm Specialists, PA

Naples, Florida, 34119, United States
National Cerebral & Cardiovascular Center Hospital

Suita, Osaka, Japan
National Taiwan University Hospital

Taipei, Taiwan
Nemocnice Na Homolce

Prague, Czechia
New York Presbyterian Hospital/Cornell University

New York, New York, 10021, United States
New York University Hospital

New York, New York, 10016, United States
New York-Presbyterian/Columbia University Medical Center

New York, New York, 10032, United States
North Shore University Hospital

Manhasset, New York, 11030, United States
Ohio Health Research Institute

Columbus, Ohio, 43214, United States
Oklahoma Heart Hospital South

Oklahoma City, Oklahoma, 73135, United States
Pacific Heart Institute

Santa Monica, California, 90404, United States
Piedmont Heart Institute

Atlanta, Georgia, 30309, United States
Prairie Education & Research Cooperative

Springfield, Illinois, 62769, United States
Premier Cardiology, Inc

Newport Beach, California, 92663, United States
Prince of Wales Hospital

Hong Kong, HK SAR, Hong Kong
Providence Hospital

Southfield, Michigan, 48075, United States
Providence Medical Foundation

Orange, California, 92868, United States
Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States
QE II Health Sciences

Halifax, Nova Scotia, B3H 3A7, Canada
Queen Mary Hospital

Hong Kong, HK SAR, Hong Kong
Royal Brompton Hospital

London, SW3 6NP, United Kingdom
Rush University Medical Center

Chicago, Illinois, 60612, United States
Sanford USD Medical Center

Sioux Falls, South Dakota, 57104, United States
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
South Denver Cardiology Associates PC

Littleton, Colorado, 80120, United States
South Texas Cardiovascular Consultants

San Antonio, Texas, 78201, United States
Southlake Regional Health Centre

Newmarket, Ontario, L3Y2P9, Canada
Sparrow Clinical Research Institute

Lansing, Michigan, 48912, United States
Texas Cardiac Arrhythmia

Austin, Texas, 78705, United States
The Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Tokyo Women's Medical University

Tokyo, Japan
USC University Hospital

Los Angeles, California, 90033, United States
UZ Gasthuisberg

Leuven, Flemish Brabant, 3000, Belgium
University of California at San Diego (UCSD) Medical Center

San Diego, California, 92118-8411, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States
University of Utah Hospital

Salt Lake City, Utah, 84132, United States
Vanderbilt Heart & Vascular Institute

Nashville, Tennessee, 37232, United States
Wake Forest University Medical Center Clinical Sciences

Winston-Salem, North Carolina, 27157, United States
Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.