Blood fats and nanoparticles may reveal hidden clues in autoimmune liver disease

NCT ID NCT07644936

Not yet recruiting Knowledge-focused Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This study looks at two types of liver disease — autoimmune hepatitis and non-alcoholic fatty liver disease — to see if fats in blood cells and tiny particles called extracellular vesicles differ between them. Researchers will collect blood samples from 24 adults and analyze these components. The goal is to find new ways to tell these diseases apart and possibly discover targets for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could identify new biomarkers to better diagnose or monitor autoimmune hepatitis without invasive biopsies.
What could go wrong: This is a small pilot study with only 24 participants, so findings may not apply broadly. It is observational and does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune hepatitis metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE HEPATITIS NON-ALCOHOLIC FATTY LIVER DISEASE

Contacts and locations

Locations

IRCCS "S. de Bellis" - Nutritional Biochemistry Lab

Castellana Grotte, Bari, 70013, Italy

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