Double heart fix: could adding valve repair to ablation beat ablation alone?

NCT ID NCT07744035

Not yet recruiting Disease control Sponsor: Mao Chen Source: ClinicalTrials.gov ↗

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial tests whether adding a minimally invasive mitral valve repair (transcatheter edge-to-edge repair, or TEER) to standard catheter ablation improves outcomes for people with both atrial functional mitral regurgitation and atrial fibrillation. Participants are randomly assigned to receive either ablation alone or ablation plus TEER during the same hospital stay. The study compares a combined measure of survival, heart-related hospitalizations, atrial fibrillation recurrence, and quality of life to see if the dual approach offers a meaningful advantage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcatheter edge-to-edge repair (TEER) plus catheter ablation
What this could lead to
If successful, this combination approach could offer a more effective treatment strategy for people with both atrial functional mitral regurgitation and atrial fibrillation, potentially reducing hospitalizations and improving quality of life.
What could go wrong
The trial is randomized but not yet conclusive; the added procedure carries risks like bleeding or device complications, and the combination may not prove superior to ablation alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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