New radioactive drug aims to destroy bladder tumors without surgery

NCT ID NCT07260162

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new drug called ATO-101 for a type of bladder cancer that hasn't responded to standard treatments. The drug delivers a short-range radioactive particle directly into the bladder to kill cancer cells while sparing healthy tissue. About 24 patients will receive the drug to find the safest dose and see if it shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ATO-101 (a radioactive antibody that targets bladder cancer cells)

What this could lead to

If it works, this could offer a new treatment option for patients with bladder cancer that hasn't responded to standard therapy, potentially avoiding bladder removal.

What could go wrong

This is a very early (Phase 1) trial with only 24 participants, so it's too soon to know if it's safe or effective. The drug uses radiation, which could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut de Cancérologie de l'Ouest

    Saint-Herblain, Loire Atlantique, 44800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••