New drug cocktail targets breast cancer brain metastases

NCT ID NCT03417544

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a combination of three drugs (atezolizumab, pertuzumab, and high-dose trastuzumab) in 19 people with HER2-positive breast cancer that had spread to the brain. The goal was to see if the treatment could shrink or control brain tumors. While the approach aims to manage the disease, ongoing treatment is typically needed, so this is not a cure.

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Conditions

The condition(s) this trial relates to.

HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States