Can aspirin be better tailored to prevent preeclampsia?
NCT ID NCT04295850
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how aspirin affects platelet function in 130 pregnant women at high risk for preeclampsia. Researchers measured platelet response and genetic factors to see if they could predict who develops high blood pressure disorders. The goal is to eventually personalize aspirin dosing for better prevention.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Aspirin 81 mg
- What this could lead to
- If successful, this could help doctors personalize aspirin doses for pregnant women to better prevent preeclampsia.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. Results may not lead to changes in clinical practice without further research.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Depression drug may mend blood vessels damaged by preeclampsia
- Postpartum blood pressure control may stop preeclampsia from leading to lifelong hypertension
- Genetic clues to severe preeclampsia could transform early detection