Aspirin's secret weapon against preeclampsia? immune cells under the microscope

NCT ID NCT04974892

Completed Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study investigated why low-dose aspirin helps prevent preeclampsia in some high-risk pregnant women but not others. Researchers took blood samples from 35 women at four points during pregnancy to study their immune cells, particularly neutrophils. The goal was to identify differences between women who responded to aspirin and those who still developed preeclampsia, which could lead to better prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help explain why low-dose aspirin prevents preeclampsia in some high-risk women but not others, potentially leading to better prevention strategies.
What could go wrong: This is a small observational study (35 participants) that only looks at immune markers, not a treatment trial. The findings may not apply to all women or lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

immune system disorder preeclampsia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNOLOGY NEUTROPHIL PREECLAMPSIA PREGNANCY

Contacts and locations

Locations

Barts Health NHS Trust, The Royal London Hospital

London, E1 1BB, United Kingdom

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